Agreement of the Heidelberg Retina Tomograph II macula edema module with fundus biomicroscopy in diabetic maculopathy.

نویسندگان

  • Mila Kisilevsky
  • Christopher Hudson
  • John G Flanagan
  • Ravi Krishna Nrusimhadevara
  • Kit Guan
  • Tien Wong
  • Mark Mandelcorn
  • Wai-Ching Lam
  • Robert G Devenyi
چکیده

OBJECTIVES To estimate the agreement between the macular edema maps (MEMs) of the Retina Module of the Heidelberg Retina Tomograph II (Heidelberg Engineering, Heidelberg, Germany) and contact lens fundus biomicroscopy (FB) and to assess the influence of combining MEM data with the results of short-wavelength automated perimetry (SWAP) and fluorescein angiography (FA) on diagnostic test performance. DESIGN Prospective, observational case series. METHODS Twenty patients (20 eyes) with diabetic retinopathy with or without clinically manifest macular edema (11 and 9 eyes, respectively) were enrolled. All patients underwent full ophthalmologic examination and also MEM assessment, SWAP, and FA. RESULTS Using FB as the "gold standard," the agreement between the MEMs and FB was very good (Kendall coefficient of concordance, 0.80). Macular edema maps showed good agreement with FA and SWAP (Kendall coefficient, 0.64 and 0.65). Virtually all of the edematous areas detected with MEM but not seen clinically had decreased sensitivity on SWAP and/or fluorescein leakage. CONCLUSIONS Macular edema maps demonstrated very good agreement with FB. Combining the results of FA and SWAP with those of the MEMs provided supporting evidence of concomitant blood-retinal barrier leakage and visual dysfunction, respectively, in areas of early retinal thickening. Prospective studies are ongoing to fully assess the diagnostic test performance of MEMs in the detection of early and progressive diabetic macular edema.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of Heidelberg Retina Tomograph II and Retinal Thickness Analyzer in the assessment of diabetic macular edema.

PURPOSE To compare the within-session variability of the Macular Edema Module of the Heidelberg Retinal Tomograph II (HRT II; Heidelberg Engineering, Heidelberg, Germany) and the Retinal Thickness Analyzer (RTA, Talia Technology Ltd., Neve-Ilan, Israel) in patients with diabetes and nondiabetic subjects and to determine the agreement of both instruments to clinical observation. METHODS Sevent...

متن کامل

Scanning laser tomography Z profile signal width as an objective index of macular retinal thickening.

AIMS (i) To evaluate the relation between retinal thickness and the Z profile signal width of a scanning laser tomographer in selected patients exhibiting clinically manifest and circumscribed macular retinal thickening; (ii) to compare the Z profile signal width values of a group of age similar normal subjects with those of the patients with macular retinal thickening; and (iii) to present the...

متن کامل

Automated Exudates Detection and Grading of Diabetic Maculopathy in Digital Retinal Images

Diabetic macular edema (DME) is a common vision threatening complication of diabetic retinopathy which can be assessed by detecting exudates (a type of bright lesion) in fundus images. Diabetes mellitus is a major cause of visual impairment and blindness. Twenty years after the onset of diabetes, almost all patients with type1 diabetes and over 60% of patients with type2 diabetes will have some...

متن کامل

The Diagnostic Function of OCT in Diabetic Maculopathy

Diabetic maculopathy (DM) is one of the major causes of vision impairment in individuals with diabetes. The traditional approach to diagnosis of DM includes fundus ophthalmoscopy and fluorescein angiography. Although very useful clinically, these methods do not contribute much to the evaluation of retinal morphology and its thickness profile. That is why a new technique called optical coherence...

متن کامل

High-resolution stereoscopic digital fundus photography versus contact lens biomicroscopy for the detection of clinically significant macular edema.

PURPOSE The purpose of this study was to compare high-resolution stereoscopic digital photography to contact lens biomicroscopy (CLBM) for the diagnosis of clinically significant macular edema. STUDY DESIGN Comparative, prospective, observational case series. PARTICIPANTS One hundred twenty diabetic patients. METHODS Patients underwent clinical retinal examination with CLBM by a retinal s...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Archives of ophthalmology

دوره 124 3  شماره 

صفحات  -

تاریخ انتشار 2006